Article
The RNA binding protein CPEB regulates dendrite morphogenesis and neuronal circuit assembly in vivo.
Proceedings of the National Academy of Sciences of the United States of America - 23 Dec 2008
Bestman Jennifer E, Cline Hollis T
Abstract excerpt
Visual system development requires experience-dependent mechanisms that regulate neuronal structure and function, including dendritic arbor growth, synapse formation, and stabilization. Although RNA binding proteins have been shown to affect some forms of synaptic plasticity in adult animals, their role in the development of neuronal structure and functional circuitry is not clear. Using two-photon time-lapse in...
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