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Article

The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus.

Journal of virology - 1 Mar 2009

Jones Daniel M, Patel Arvind H, Targett-Adams Paul, McLauchlan John

Abstract excerpt

Studies of the hepatitis C virus (HCV) life cycle have been aided by development of in vitro systems that enable replication of viral RNA and production of infectious virus. However, the functions of the individual proteins, especially those engaged in RNA replication, remain poorly understood. It is considered that NS4B, one of the replicase components, creates sites for genome synthesis, which appear as...

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Share to Endoplasmic Reticulum
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Complementation Test

Share to Protein Processing, Post-Translational

Share to RNA-Dependent RNA Polymerase

Share to Viral Nonstructural Proteins

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Source

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Identifiers

PMID: 19073716
DOI: 10.1128/JVI.01885-08
PMCID: PMC2643717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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