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Hepatitis C Viral Replication Complex

22 Mar 2021

Abstract excerpt

The life cycle of the hepatitis C virus (HCV) can be divided into several stages, including viral entry, protein translation, RNA replication, viral assembly, and release. HCV genomic RNA replication occurs in the replication organelles (RO) and is tightly linked to ER membrane alterations containing replication complexes (proteins NS3 to NS5B). The amplification of HCV genomic RNA could be regulated by the RO...

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PMID: 33809897
DOI: 10.3390/v13030520

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