Article
The +347 C promoter allele up-regulates MAPT expression and is associated with Alzheimer's disease among the Chinese Han.
Neuroscience letters - 6 Feb 2009
Sun Wenjun, Jia Jianping
Abstract excerpt
The microtubule-associated protein tau has been known to be associated with the pathogenesis of Alzheimer's disease (AD). We identified a novel single nucleotide polymorphism (SNP) in the promoter region of the microtubule-associated protein tau gene (MAPT) in Chinese Han population: 347G/C. The...
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