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Article

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations

1 Dec 2008

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19070574
DOI: 10.1016/j.cell.2008.09.062

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH TranslocationsPMID 19070574Read ↗

AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutationSemantic proximity Read ↗

The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks.Semantic proximity Read ↗

IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomasSemantic proximity Read ↗

A role for AID in chromosome translocations between c-myc and the IgH variable regionSemantic proximity Read ↗

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.Semantic proximity Read ↗

AID expression levels determine the extent of <i>cMyc</i> oncogenic translocations and the incidence of B cell tumor developmentSemantic proximity Read ↗

MRE11/RAD50 Cleaves DNA in the AID/UNG-Dependent Pathway of Immunoglobulin Gene DiversificationSemantic proximity Read ↗

AID is required for germinal center–derived lymphomagenesisSemantic proximity Read ↗

Activation-induced Cytidine Deaminase in B Cell Immunity and CancersSemantic proximity Read ↗

The off-target effects of AID in carcinogenesisSemantic proximity Read ↗

[AID controls immunoglobulin class switch recombination].Semantic proximity Read ↗

Role of the translocation partner in protection against AID-dependent chromosomal translocationsSemantic proximity Read ↗

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