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Article

Calcium-sensing receptor gene polymorphisms in patients with calcium nephrolithiasis.

Current opinion in nephrology and hypertension - 1 Jul 2012

Vezzoli Giuseppe, Terranegra Annalisa, Soldati Laura

Abstract excerpt

PURPOSE OF REVIEW: The calcium-sensing receptor gene (CaSR, chr. 3q13.3-21) is a candidate to explain nephrolithiasis. This review analyzes the potential role of CaSR in lithogenesis according to findings of functional and genetic studies. RECENT FINDINGS: CaSR is a cation receptor located in the tubular cell plasma membrane. Its activation decreases calcium reabsorption in the ascending limb and distal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Calcium-Sensing

Share to Regulatory Sequences, Nucleic Acid

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Source

Identifiers

PMID: 22660550
DOI: 10.1097/MNH.0b013e3283542290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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