Article
BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis.
Familial cancer - 1 Jan 2006
Foulkes William D
Abstract excerpt
BRCA1 and BRCA2 are important breast and ovarian cancer susceptibility genes, and mutations in these two genes confer lifetime risks of breast cancer of up to 80% and ovarian cancer risks of up to 40%. Clinico-pathological studies have identified features that are specific to BRCA1-related breast cancer, but this has been more difficult for BRCA2-related breast cancer. Ovarian cancers due to BRCA1 or BRCA2...
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