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Article

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.

Journal of molecular biology - 6 Feb 2009

Shin David S, Didonato Michael, Barondeau David P, Hura Greg L, Hitomi Chiharu, Berglund J Andrew, Getzoff Elizabeth D, Cary S Craig, Tainer John A

Abstract excerpt

Prokaryotic thermophiles supply stable human protein homologs for structural biology; yet, eukaryotic thermophiles would provide more similar macromolecules plus those missing in microbes. Alvinella pompejana is a deep-sea hydrothermal-vent worm that has been found in temperatures averaging as hi...

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Identifiers

PMID: 19063897
DOI: 10.1016/j.jmb.2008.11.031
PMCID: PMC2669833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19063897-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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