Article
[Specific immune against pancreatic cancer induced by dendritic cells pulsed with mutant K-ras peptide].
Zhonghua yi xue za zhi - 22 Jul 2008
Yang Bo, He Yang, Sun Dong-lin, Zou Yan, Qin Xi-hu, Huang Bo-hua
Abstract excerpt
OBJECTIVE: To investigate whether dendritic cells (DCs) pulsed with mutant K-ras peptide (12-Val) can induce efficiently specific anti-tumor immune response against pancreatic cancer. METHODS: Immature DCs were isolated from the peripheral blood of a volunteer and were pulsed with synthesized mutant K-ras peptide (YKLVVVGAV). When the DCs were matured the expression rate of Kras antigen epitope on the DC's...
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