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Article

Exogenous iron increases hemoglobin in beta-thalassemic mice.

Experimental hematology - 1 Feb 2009

Ginzburg Yelena Z, Rybicki Anne C, Suzuka Sandra M, Hall Charles B, Breuer William, Cabantchik Z Ioav, Bouhassira Eric E, Fabry Mary E, Nagel Ronald L

Abstract excerpt

OBJECTIVE: Beta-thalassemia results from beta-globin gene mutations that lead to ineffective erythropoiesis, shortened red cell survival, and anemia. Patients with beta-thalassemia develop iron overload, despite which, hepcidin levels are low. This suggests that hepcidin regulation in beta-thalassemia is more sensitive to factors unrelated to iron state. Our preliminary data demonstrates that Hbb(th1/th1) mice, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19059700
DOI: 10.1016/j.exphem.2008.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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