Article
Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration.
Molecular vision - 1 Jan 2008
Ahmed Zubair M, Kjellstrom Sten, Haywood-Watson Ricky J L, Bush Ronald A, Hampton Lori L, Battey James F, Riazuddin Saima, Frolenkov Gregory, Sieving Paul A, Friedman Thomas B
Abstract excerpt
PURPOSE: To determine whether cadherin 23 and protocadherin 15 can substitute for one another in the maintenance of the retina and other tissues in the mouse. Does homozygosity for both v and av mutant alleles (i.e., a double homozygous mouse) cause retinal degeneration or an obvious retinal hist...
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