Article
GOSR2 Lys67Arg is associated with hypertension in whites.
American journal of hypertension - 1 Feb 2009
Meyer Tamra E, Shiffman Dov, Morrison Alanna C, Rowland Charles M, Louie Judy Z, Bare Lance A, Ross David A, Arellano Andre R, Chasman Daniel I, Ridker Paul M, Pankow James S, Coresh Josef, Malloy Mary J, Kane John P, Ellis Stephen G, Devlin James J, Boerwinkle Eric
Abstract excerpt
BACKGROUND: Hypertension is a risk factor for coronary heart disease (CHD), but the causes of hypertension remain largely unknown. Genetic variation is thought to contribute to the etiology of hypertension. We tested a single-nucleotide polymorphism (SNP) (Lys67Arg, rs197922) in the Golgi SNAP Receptor Complex Member 2 (GOSR2) gene for association with hypertension and blood pressure (BP). We chose this SNP...
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