Article
Substantial advantage of a combined Bayesian and genotyping approach in testosterone doping tests.
Steroids - 1 Mar 2009
Schulze Jenny Jakobsson, Lundmark Jonas, Garle Mats, Ekström Lena, Sottas Pierre-Edouard, Rane Anders
Abstract excerpt
Testosterone abuse is conventionally assessed by the urinary testosterone/epitestosterone (T/E) ratio, levels above 4.0 being considered suspicious. A deletion polymorphism in the gene coding for UGT2B17 is strongly associated with reduced testosterone glucuronide (TG) levels in urine. Many of the individuals devoid of the gene would not reach a T/E ratio of 4.0 after testosterone intake. Future test programs...
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