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Article

Pleiotropic scaling and QTL data.

Nature - 4 Dec 2008

Hermisson Joachim, McGregor Alistair P

Abstract excerpt

Wagner et al. have recently introduced much-needed data to the debate on how complexity of the genotype-phenotype map affects the distribution of mutational effects. They used quantitative trait loci (QTLs) mapping analysis of 70 skeletal characters in mice and regressed the total QTL effect on the number of traits affected (level of pleiotropy). From their results they suggest that mutations with higher...

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PMID: 19052568
DOI: 10.1038/nature07452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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