Article
A large-sample QTL study in mice: I. Growth.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2004
Rocha Joao L, Eisen Eugene J, Van Vleck L Dale, Pomp Daniel
Abstract excerpt
By use of long-term selection lines for high and low growth, a large-sample (n = approximately 1,000 F2) experiment was conducted in mice to further understand the genetic architecture of complex polygenic traits. In combination with previous work, we conclude that QTL analysis has reinforced classic polygenic paradigms put in place prior to molecular analysis. Composite interval mapping revealed large numbers of...
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