Article
Is the genotype-phenotype map modular? A statistical approach using mouse quantitative trait loci data.
Genetics - 1 Sept 2000
Mezey J G, Cheverud J M, Wagner G P
Abstract excerpt
Various theories about the evolution of complex characters make predictions about the statistical distribution of genetic effects on phenotypic characters, also called the genotype-phenotype map. With the advent of QTL technology, data about these distributions are becoming available. In this article, we propose simple tests for the prediction that functionally integrated characters have a modular...
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