Article
Effects of Helicobacter pylori infection on genetic instability, the aberrant CpG island methylation status and the cellular phenotype in Barrett's esophagus in a Japanese population.
International journal of cancer - 15 Mar 2009
Moriichi Kentaro, Watari Jiro, Das Kiron M, Tanabe Hiroki, Fujiya Mikihiro, Ashida Toshifumi, Kohgo Yutaka
Abstract excerpt
Genetic or epigenetic alterations in Barrett's esophagus (BE) with/without Helicobacter pylori (H. pylori) infection remain unclear. We examined the effects of H. pylori infection on genetic instability (GIN), the CpG island methylation status and a biomarker related to BE carcinogenesis. We analyzed 113 Japanese individuals with endoscopically suspected BE. The patients included, Group CLE (n = 25): no...
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