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Article

A new amyloid-like beta-aggregate with amyloid characteristics, except fibril morphology.

Journal of molecular biology - 30 Jan 2009

Chang Evan S-H, Liao Tai-Yan, Lim Tsong-Shin, Fann Wunshain, Chen Rita P-Y

Abstract excerpt

Amyloid plaques, formed from amyloid beta (Abeta) peptides (mainly Abeta40 or Abeta42), are one of the most important pathological characteristics of Alzheimer's disease. Here, a single D-form proline substitution in the 40-amino-acid Abeta40 peptide can totally change the aggregation behavior of this peptide. The residue immediately preceding each glycine in Abeta40 (S8, V24, I32, and V36) was individually...

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Identifiers

PMID: 19041877
DOI: 10.1016/j.jmb.2008.11.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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