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Article

Phosphorylation of DeltaFosB mediates its stability in vivo.

Neuroscience - 23 Jan 2009

Ulery-Reynolds P G, Castillo M A, Vialou V, Russo S J, Nestler E J

Abstract excerpt

The transcription factor, DeltaFosB, accumulates in a region-specific manner in brain in response to many types of chronic stimulation due to the unusual stability of the protein. The phosphorylation of Ser27 in DeltaFosB has been shown to promote this stability in vitro. We show here that this phosphorylation reaction is also important for DeltaFosB's stability in the brain in vivo and for the unique behavioral...

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Identifiers

PMID: 19041372
DOI: 10.1016/j.neuroscience.2008.10.059
PMCID: PMC2734485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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