Article
Inherited primary hypothyroidism with thyrotrophin resistance in Japanese cats.
The Journal of endocrinology - 1 May 1991
Tanase H, Kudo K, Horikoshi H, Mizushima H, Okazaki T, Ogata E
Abstract excerpt
Mutant cats were developed with non-goitrous primary hypothyroidism. They were clinically characterized by severely retarded growth, mild anaemia and high mortality in the young. They responded markedly to thyroid hormone replacement. Thyroid glands in the mutants were normal in position but slig...
Topics
- Animals
- Body Weight
- Cats
- Disease Models, Animal
- Female
- Genes, Recessive
- Hypothyroidism
- Male
- Mutation
- Thyroid Hormones
- Thyrotropin
- Thyrotropin-Releasing Hormone
