Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited primary hypothyroidism with thyrotrophin resistance in Japanese cats.

The Journal of endocrinology - 1 May 1991

Tanase H, Kudo K, Horikoshi H, Mizushima H, Okazaki T, Ogata E

Abstract excerpt

Mutant cats were developed with non-goitrous primary hypothyroidism. They were clinically characterized by severely retarded growth, mild anaemia and high mortality in the young. They responded markedly to thyroid hormone replacement. Thyroid glands in the mutants were normal in position but slightly reduced in size. Laboratory studies revealed low serum concentrations of thyroxine (T4) and tri-iodothyronine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Weight
Share to Cats
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Recessive

Share to Hypothyroidism

Share to Mutation

Share to Thyroid Hormones

Share to Thyrotropin

Source

Identifiers

PMID: 1904088
DOI: 10.1677/joe.0.1290245

Genes

TRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited primary hypothyroidism with thyrotrophin resistance in Japanese cats.PMID 1904088Read ↗

[Familial congenital hypothyroidism due to loss of function mutation of the thyrotropin receptor (resistance to thyrotropin)].Semantic proximity Read ↗

Novel insight from transgenic mice into thyroid hormone resistance and the regulation of thyrotropin.Semantic proximity Read ↗

A mouse model demonstrates a multigenic origin of congenital hypothyroidism.Semantic proximity Read ↗

A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor.Semantic proximity Read ↗

The syndrome of resistance to thyroid stimulating hormone.Semantic proximity Read ↗

Central Hypothyroidism in Miniature Schnauzers.Semantic proximity Read ↗

Clinical significance of heterozygous carriers associated with compensated hypothyroidism in R450H, a common inactivating mutation of the thyrotropin receptor gene in Japanese.Semantic proximity Read ↗

CNS hypomyelination in Rat Terrier dogs with congenital goiter and a mutation in the thyroid peroxidase gene.Semantic proximity Read ↗

Functional mutations in the thyroid-stimulating hormone receptor in natural stickleback populations at sites identical to human disease-causing mutations.Semantic proximity Read ↗

Requirement of thyrotropin-releasing hormone for the postnatal functions of pituitary thyrotrophs: ontogeny study of congenital tertiary hypothyroidism in mice.Semantic proximity Read ↗

Mice lacking the thyrotropin-releasing hormone gene: what do they tell us?Semantic proximity Read ↗

Familial unresponsiveness to thyrotropin by autosomal recessive inheritance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.