Article
Size- and distance-dependent nanoparticle surface-energy transfer (NSET) method for selective sensing of hepatitis C virus RNA.
Chemistry (Weinheim an der Bergstrasse, Germany) - 1 Jan 2009
Griffin Jelani, Singh Anant Kumar, Senapati Dulal, Rhodes Patsy, Mitchell Kanieshia, Robinson Brianica, Yu Eugene, Ray Paresh Chandra
Abstract excerpt
We report size- and distance-dependent surface-energy transfer (SET) properties of gold nanoparticles for recognizing hepatitis C virus (HCV) RNA sequence sensitively and selectively (single-base mutations) in a homogeneous format. We have demonstrated that quenching efficiency increases by three orders of magnitude, as the particle size increases from 5 to 70 nm. Due to this extraordinarily high K(SV),...
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