Article
Sea-urchin-like Au nanocluster with surface-enhanced raman scattering in detecting epidermal growth factor receptor (EGFR) mutation status of malignant pleural effusion.
ACS applied materials & interfaces - 14 Jan 2015
Wang Lei, Guo Ting, Lu Qiang, Yan Xiaolong, Zhong Daixing, Zhang Zhipei, Ni Yunfeng, Han Yong, Cui Daxiang, Li Xiaofei, Huang Lijun
Abstract excerpt
Somatic mutations in the epidermal growth factor receptor (EGFR) gene are common in patients with lung adenocarcinomas and are associated with sensitivity to the small-molecule tyrosine kinase inhibitors (TKIs). For 10%-50% of the patients who experienced malignant pleural effusion (MPE), patholo...
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