Article
Identification of possible candidate genes regulating Sjögren's syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy.
Arthritis research & therapy - 1 Jan 2008
Nguyen Cuong Q, Cornelius Janet G, Cooper Lauren, Neff Jonathan, Tao Joann, Lee Byung Ha, Peck Ammon B
Abstract excerpt
INTRODUCTION: Sjögren syndrome (SjS) is a systemic autoimmune disease in which an immunological attack primarily against the salivary and lacrimal glands results in the loss of acinar cell tissue and function, leading to stomatitis sicca and keratoconjunctivitis sicca. In recent years, two genetic regions, one on chromosome 1 (designated autoimmune exocrinopathy 2 or Aec2) and the second on chromosome 3...
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