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Article

Hemolytic and antimicrobial activities of the twenty-four individual omission analogues of melittin.

Biochemistry - 14 May 1991

Blondelle S E, Houghten R A

Abstract excerpt

Although melittin's hemolytic activity has been extensively studied, the orientation of membrane-bound melittin remains uncertain. We have investigated the effect of individually omitted amino acid residues on melittin's activity and related these results to the existing models of melittin-membrane interaction. The extent of hemolysis of the omission analogues closely followed the four known conformational...

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PMID: 1903066
DOI: 10.1021/bi00233a006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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