Article
Mammographic breast density--evidence for genetic correlations with established breast cancer risk factors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008
Douglas Julie A, Roy-Gagnon Marie-Hélène, Zhou Chuan, Mitchell Braxton D, Shuldiner Alan R, Chan Heang-Ping, Helvie Mark A
Abstract excerpt
Previous twin and family studies indicate that the familial aggregation of breast density is due (in part) to genetic factors. Whether these genetic influences are shared with other breast cancer risk factors, however, is not known. Using standard film-screen mammography, we screened 550 women, including 611 pairs of sisters, from the Old Order Amish population of Lancaster County, Pennsylvania. We digitized...
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