Article
Explaining variance in the cumulus mammographic measures that predict breast cancer risk: a twins and sisters study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2013
Nguyen Tuong L, Schmidt Daniel F, Makalic Enes, Dite Gillian S, Stone Jennifer, Apicella Carmel, Bui Minh, Macinnis Robert J, Odefrey Fabrice, Cawson Jennifer N, Treloar Susan A, Southey Melissa C, Giles Graham G, Hopper John L
Abstract excerpt
BACKGROUND: Mammographic density, the area of the mammographic image that appears white or bright, predicts breast cancer risk. We estimated the proportions of variance explained by questionnaire-measured breast cancer risk factors and by unmeasured residual familial factors. METHODS: For 544 MZ and 339 DZ twin pairs and 1,558 non-twin sisters from 1,564 families, mammographic density was measured using the...
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