Article
The relative importance of genetics and environment on mammographic density.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2009
Ursin Giske, Lillie Elizabeth O, Lee Eunjung, Cockburn Myles, Schork Nicholas J, Cozen Wendy, Parisky Yuri R, Hamilton Ann S, Astrahan Melvin A, Mack Thomas
Abstract excerpt
BACKGROUND: Although several environmental factors predict mammographic density, estimates of its heritability have been quite high. We investigated whether part of the presumed heritability might be attributed to differential sharing of modifiable risk factors in monozygotic (MZ) and dizygotic (DZ) twins. METHODS: We measured percent and absolute mammographic density using mammograms from 257 MZ and 296 DZ twin...
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