Article
Characterization of basal-like subtype in a Danish consecutive primary breast cancer cohort.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2018
Kinalis Savvas, Nielsen Finn Cilius, Talman Maj-Lis, Ejlertsen Bent, Rossing Maria
Abstract excerpt
BACKGROUND: Transcriptome analysis enables classification of breast tumors into molecular subtypes. BRCA1/2 predisposed patients are more likely to suffer from a basal-like subtype and this group of patients displays a more distinct phenotype and genotype. Hence, in-depth characterization of this separate entity is needed. MATERIAL AND METHODS: Molecular subtyping was performed on a consecutive and unselected...
Topics
- Age Factors
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Cohort Studies
- Denmark
- Female
- Hedgehog Proteins
- Heterozygote
- Humans
- Middle Aged
- Mutation