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Article

Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper.

Endocrinology - 1 Apr 2009

Bousquet-Moore D, Ma X M, Nillni E A, Czyzyk T A, Pintar J E, Eipper B A, Mains R E

Abstract excerpt

Amidated peptides are critically involved in many physiological functions. Genetic deletion of peptidylglycine alpha-amidating monooxygenase (PAM), the only enzyme that can synthesize these peptides, is embryonically lethal. The goal of the present study was the identification of physiological fu...

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Identifiers

PMID: 19022883
DOI: 10.1210/en.2008-1202
PMCID: PMC2659272

Genes

PAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19022883-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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