EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib.

doi:10.1007/s00432-008-0512-1

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Article

EGFR mutations and HER2/3 protein expression and clinical outcome in Chinese advanced non-small cell lung cancer patients treated with gefitinib.

Journal of cancer research and clinical oncology - 1 Jun 2009

Xu Jian Ming, Han Yu, Duan Hai Qing, Gao E Mei, Zhang Yang, Liu Xiao Qing, Zhang Jing Sheng, Toschi Luca, Galetta Domenico, Azzariti Amalia, Paradiso Angelo

Abstract excerpt

BACKGROUND: To assess the role of various epidermal growth factor receptor (EGFR) mutations and HER2/3 protein expression as predictive markers of responsiveness to gefitinib therapy in Chinese patients with advanced non-small cell lung cancer (NSCLC). METHODS: A total of 106 Chinese NSCLC patien...

Topics

Adult
Aged
Antineoplastic Agents
Carcinoma, Non-Small-Cell Lung
China
DNA Mutational Analysis
ErbB Receptors
Female
Gefitinib
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Lung
Lung Neoplasms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Quinazolines

Source

Open in PubMed

Identifiers

PMID: 19020901
DOI: 10.1007/s00432-008-0512-1

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19020901-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.