Article
EGFR mutations are associated with prognosis but not with the response to front-line chemotherapy in the Chinese patients with advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2010
Wu Meina, Zhao Jun, Song Sonya Wei, Zhuo Minglei, Wang Xin, Bai Hua, Wang Shuhang, Yang Lu, An Tongtong, Zhang Yan, Duan Jianchun, Wang Yuyan, Guo Qingzhi, Liu Xuyi, Liu Ninghong, Wang Jie
Abstract excerpt
The study aimed to investigate associations of tumor tissue EGFR mutations with response to the front-line chemotherapy and prognosis in advanced non-small cell lung cancer (NSCLC) patients. EGFR genotypes of 145 chemotherapy-naive patients with Stage IIIB and IV NSCLC were examined by using denaturing high-performance liquid chromatography (DHPLC). All patients received the front-line chemotherapy. There were 69...
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