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Article

Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

The British journal of dermatology - 1 Feb 2009

Warren R B, Smith R L, Campalani E, Eyre S, Smith C H, Barker J N W N, Worthington J, Griffiths C E M

Abstract excerpt

BACKGROUND: The use of methotrexate is limited by interindividual variability in response. Previous studies in patients with either rheumatoid arthritis or psoriasis suggest that genetic variation across the methotrexate metabolic pathway might enable prediction of both efficacy and toxicity of the drug. OBJECTIVES: To assess if single nucleotide polymorphisms (SNPs) across four genes that are relevant to...

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Source

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Identifiers

PMID: 19016697
DOI: 10.1111/j.1365-2133.2008.08898.x
PMCID: PMC2680291

Genes

ATIC
FPGS
GGH
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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