Article
Reinventing the ames test as a quantitative lab that connects classical and molecular genetics.
Genetics - 1 Jan 2009
Goodson-Gregg Nathan, De Stasio Elizabeth A
Abstract excerpt
While many institutions use a version of the Ames test in the undergraduate genetics laboratory, students typically are not exposed to techniques or procedures beyond qualitative analysis of phenotypic reversion, thereby seriously limiting the scope of learning. We have extended the Ames test to include both quantitative analysis of reversion frequency and molecular analysis of revertant gene sequences. By giving...
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