Article
Connecting common genetic polymorphisms to protein function: A modular project sequence for lecture or lab.
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology - 12 Nov 2016
Berndsen Christopher E, Young Byron H, McCormick Quinlin J, Enke Raymond A
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in DNA can result in phenotypes where the biochemical basis may not be clear due to the lack of protein structures. With the growing number of modeling and simulation software available on the internet, students can now participate in determining how small changes in genetic information impact cellular protein structure and function. We have developed a modular series of...
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