Article
Supportive evidence for reduced expression of GNB1L in schizophrenia.
Schizophrenia bulletin - 1 Jul 2010
Ishiguro Hiroki, Koga Minori, Horiuchi Yasue, Noguchi Emiko, Morikawa Miyuki, Suzuki Yoshimi, Arai Makoto, Niizato Kazuhiro, Iritani Shyuji, Itokawa Masanari, Inada Toshiya, Iwata Nakao, Ozaki Norio, Ujike Hiroshi, Kunugi Hiroshi, Sasaki Tsukasa, Takahashi Makoto, Watanabe Yuichiro, Someya Toshiyuki, Kakita Akiyoshi, Takahashi Hitoshi, Nawa Hiroyuki, Arinami Tadao
Abstract excerpt
BACKGROUND: Chromosome 22q11 deletion syndrome (22q11DS) increases the risk of development of schizophrenia more than 10 times compared with that of the general population, indicating that haploinsufficiency of a subset of the more than 20 genes contained in the 22q11DS region could increase the risk of schizophrenia. In the present study, we screened for genes located in the 22q11DS region that are expressed at...
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