Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Gene-Expression Analysis Shows Involvement of Schizophrenia-Relevant Pathways in Patients with 22q11 Deletion Syndrome

22 Mar 2012

Abstract excerpt

22q11 Deletion Syndrome (22q11DS) is associated with dysmorphology and a high prevalence of schizophrenia-like symptoms. Several genes located on chromosome 22q11 have been linked to schizophrenia. The deletion is thought to disrupt the expression of multiple genes involved in maturation and development of neurons and neuronal circuits, and neurotransmission. We investigated whole-genome gene expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Fibrosis and Remodeling
Share to Congenital heart defects research
Share to Genetic Mapping and Diversity in Plants and Animals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22457764
DOI: 10.1371/journal.pone.0033473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Gene-Expression Analysis Shows Involvement of Schizophrenia-Relevant Pathways in Patients with 22q11 Deletion SyndromePMID 22457764Read ↗

Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletionSemantic proximity Read ↗

A neurogenetic model for the study of schizophrenia spectrum disorders: the International 22q11.2 Deletion Syndrome Brain Behavior Consortium.Semantic proximity Read ↗

The 22q11.2 region regulates presynaptic gene-products linked to schizophreniaSemantic proximity Read ↗

Exploring pathway interactions to detect molecular mechanisms of disease: 22q11.2 deletion syndrome.Semantic proximity Read ↗

miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndromeSemantic proximity Read ↗

Exploring Pathway Interactions to Detect Molecular Mechanisms of Disease: 22q11.2 Deletion SyndromeSemantic proximity Read ↗

Analysis of induced pluripotent stem cells carrying 22q11.2 deletion.Semantic proximity Read ↗

22q11 deletion syndrome: a review of the neuropsychiatric features and their neurobiological basisSemantic proximity Read ↗

Review: Genes Involved in Mitochondrial Physiology Within 22q11.2 Deleted Region and Their Relevance to SchizophreniaSemantic proximity Read ↗

Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes.Semantic proximity Read ↗

Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia.Semantic proximity Read ↗

Functional consequences of genetic risk for neuropsychiatric conditions at chr22qSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.