Article
High levels of local inter- and intra-host genetic variation of West Nile virus and evidence of fine-scale evolutionary pressures.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2017
Ehrbar Dylan J, Ngo Kiet A, Campbell Scott R, Kramer Laura D, Ciota Alexander T
Abstract excerpt
West Nile virus (WNV; Flaviviridae, Flavivirus) has been endemic in New York State (NYS) since its 1999 introduction, yet prevalence in Culex mosquitoes varies substantially over small spatial and temporal scales. It is unclear if viral genetics plays a role in this variability, as genetic and phenotypic characterization on local scales has generally been lacking. In addition, intrahost diversity of circulating...
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