Article
Archival Isolates Confirm a Single Topotype of West Nile Virus in Australia.
PLoS neglected tropical diseases - 1 Dec 2016
Huang Bixing, Prow Natalie A, van den Hurk Andrew F, Allcock Richard J N, Moore Peter R, Doggett Stephen L, Warrilow David
Abstract excerpt
West Nile virus is globally wide-spread and causes significant disease in humans and animals. The evolution of West Nile virus Kunjin subtype in Australia (WNVKUN) was investigated using archival samples collected over a period of 50 years. Based on the pattern of fixed amino acid substitutions and time-stamped molecular clock analyses, a single long-term lineage (or topotype) was inferred. This implies that a...
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