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Article

Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation.

The Journal of biological chemistry - 9 Jan 2009

Lafrance-Vanasse Julien, Lefebvre Maryse, Di Lello Paola, Sygusch Jurgen, Omichinski James G

Abstract excerpt

Bacteria resistant to methylmercury utilize two enzymes (MerA and MerB) to degrade methylmercury to the less toxic elemental mercury. The crucial step is the cleavage of the carbon-mercury bond of methylmercury by the organomercurial lyase (MerB). In this study, we determined high resolution crys...

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Identifiers

PMID: 19004822
DOI: 10.1074/jbc.M807143200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19004822-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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