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Article

Combining effects of polymorphism of tumor necrosis factor alpha 5'-flanking region and HLA-DRB1 on radiological progression in patients with rheumatoid arthritis.

Modern rheumatology - 1 Jan 2009

Ichikawa Naomi, Kotake Shigeru, Hakoda Masayuki, Higami Kenshi, Kawasaki Aya, Furuya Takefumi, Nanke Yuki, Tsuchiya Naoyuki, Tokunaga Katsushi, Kamatani Naoyuki

Abstract excerpt

We examined whether polymorphisms upstream of the TNF-alpha gene (TNFA) were associated with the radiological progression of rheumatoid arthritis (RA). One hundred and twenty-three patients with early RA (disease duration <1 year) were enrolled in a prospective follow-up study. The laboratory fin...

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Source

Identifiers

PMID: 19002558
DOI: 10.1007/s10165-008-0134-0

Genes

CRP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19002558-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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