Article
IL10 GGC haplotype is positively and HLA-DQA1*05-DQB1*02 is negatively associated with radiographic progression in undifferentiated arthritis.
The Journal of rheumatology - 1 Jul 2010
Ursum Jennie, van der Weijden Mignon A C, van Schaardenburg Dirkjan, Prins Arend P A, Dijkmans Ben A C, Twisk Jos W R, Crusius Jakob B A, van der Horst-Bruinsma Irene E
Abstract excerpt
OBJECTIVE: In rheumatoid arthritis (RA), many genetic markers, such as the shared-epitope (SE) alleles, are described in association with radiographic progression, but limited data are available on undifferentiated arthritis (UA). We investigated whether single-nucleotide polymorphisms (SNP) and haplotypes in immune response genes and HLA class II alleles are associated with radiographic progression in patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
