Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the tau gene region chromosome inversion in progressive supranuclear palsy, corticobasal degeneration, and related disorders.

Archives of neurology - 1 Nov 2008

Webb Amy, Miller Bruce, Bonasera Stephen, Boxer Adam, Karydas Anna, Wilhelmsen Kirk C

Abstract excerpt

BACKGROUND: An inverted region on chromosome 17 has been previously linked to many Pick complex diseases. Due to the inversion, an exact causal locus has been difficult to identify, but the microtubule-associated protein tau gene is a likely candidate gene for its involvement in these diseases with tau inclusion. OBJECTIVE: To search for variants that confer susceptibility to 4 tauopathies and clinically related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basal Ganglia
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Inversion

Share to Chromosomes, Human, Pair 17

Share to Dementia

Share to Supranuclear Palsy, Progressive

Share to tau Proteins

Share to Tauopathies

Source

Open in PubMed Open full text

Identifiers

PMID: 19001166
DOI: 10.1001/archneur.65.11.1473
PMCID: PMC2680206

Genes

MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the tau gene region chromosome inversion in progressive supranuclear palsy, corticobasal degeneration, and related disorders.PMID 19001166Read ↗

Untangling the tau gene association with neurodegenerative disordersSemantic proximity Read ↗

The structure of the tau haplotype in controls and in progressive supranuclear palsy.Semantic proximity Read ↗

Unraveling the complex role of MAPT-containing H1 and H2 haplotypes in neurodegenerative diseases.Semantic proximity Read ↗

Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and<i>MAPT</i>Sub-haplotypesSemantic proximity Read ↗

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.Semantic proximity Read ↗

MAPT haplotype-associated transcriptomic changes in progressive supranuclear palsySemantic proximity Read ↗

Refining frontotemporal dementia with parkinsonism linked to chromosome 17: introducing FTDP-17 (MAPT) and FTDP-17 (PGRN).Semantic proximity Read ↗

Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conferenceSemantic proximity Read ↗

Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration.Semantic proximity Read ↗

Genetic bases of Progressive Supranuclear Palsy: the MAPT tau disease.Semantic proximity Read ↗

Clinical and Pathological Features of FTDP-17 with MAPT p.K298_H299insQ Mutation.Semantic proximity Read ↗

Genetics of Progressive Supranuclear PalsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.