Article
Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients.
Rheumatology international - 1 May 2009
Dai Yong, Sui Weiguo, Lan Huijuan, Yan Qiang, Huang He, Huang YuanShuai
Abstract excerpt
MicroRNAs (miRNAs) are noncoding RNA molecules of 21-24 nt that regulate the expression of target genes in a post-transcriptional manner. Evidence indicates that miRNAs play essential roles in embryogenesis, cell differentiation, and pathogenesis of human diseases. This study describes a comparison between the miRNA profile of kidney biopsies from lupus nephritis (LN) patients and the controls, to develop further...
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