Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system.

PLoS genetics - 1 Nov 2008

Romero-Calderón Rafael, Uhlenbrock Guido, Borycz Jolanta, Simon Anne F, Grygoruk Anna, Yee Susan K, Shyer Amy, Ackerson Larry C, Maidment Nigel T, Meinertzhagen Ian A, Hovemann Bernhard T, Krantz David E

Abstract excerpt

Unlike other monoamine neurotransmitters, the mechanism by which the brain's histamine content is regulated remains unclear. In mammals, vesicular monoamine transporters (VMATs) are expressed exclusively in neurons and mediate the storage of histamine and other monoamines. We have studied the visual system of Drosophila melanogaster in which histamine is the primary neurotransmitter released from photoreceptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histamine

Share to Neuroglia

Share to Optic Lobe, Nonmammalian

Share to Protein Isoforms

Share to RNA Splicing

Share to Vesicular Monoamine Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 18989452
DOI: 10.1371/journal.pgen.1000245
PMCID: PMC2570955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system.PMID 18989452Read ↗

Drosophila ABC transporter mutants white, brown and scarlet have altered contents and distribution of biogenic amines in the brain.Semantic proximity Read ↗

Histamine-like immunoreactivity in the visual system and brain of Drosophila melanogaster.Semantic proximity Read ↗

The metabolism of histamine in the Drosophila optic lobe involves an ommatidial pathway: β-alanine recycles through the retina.Semantic proximity Read ↗

Transgenic line for the identification of cholinergic release sites in Drosophila melanogaster.Semantic proximity Read ↗

Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin.Semantic proximity Read ↗

Distinct roles for two histamine receptors (hclA and hclB) at the Drosophila photoreceptor synapse.Semantic proximity Read ↗

A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns.Semantic proximity Read ↗

tan and ebony genes regulate a novel pathway for transmitter metabolism at fly photoreceptor terminals.Semantic proximity Read ↗

Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections.Semantic proximity Read ↗

A putative vesicular transporter expressed in Drosophila mushroom bodies that mediates sexual behavior may define a neurotransmitter system.Semantic proximity Read ↗

Histamine-HisCl1 receptor axis regulates wake-promoting signals in Drosophila melanogaster.Semantic proximity Read ↗

Selective histamine uptake rescues photo- and mechanoreceptor function of histidine decarboxylase-deficient Drosophila mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.