Article
A putative vesicular transporter expressed in Drosophila mushroom bodies that mediates sexual behavior may define a neurotransmitter system.
Neuron - 20 Oct 2011
Brooks Elizabeth S, Greer Christina L, Romero-Calderón Rafael, Serway Christine N, Grygoruk Anna, Haimovitz Jasmine M, Nguyen Bac T, Najibi Rod, Tabone Christopher J, de Belle J Steven, Krantz David E
Abstract excerpt
Vesicular transporters are required for the storage of all classical and amino acid neurotransmitters in synaptic vesicles. Some neurons lack known vesicular transporters, suggesting additional neurotransmitter systems remain unidentified. Insect mushroom bodies (MBs) are critical for several behaviors, including learning, but the neurotransmitters released by the intrinsic Kenyon cells (KCs) remain unknown....
Topics
- Animals
- Drosophila
- Drosophila Proteins
- Mushroom Bodies
- Mutation
- Neurons
- Sexual Behavior, Animal
- Synaptic Transmission
- Synaptic Vesicles
- Vesicular Transport Proteins