Article
Structural and functional characterization of the LldR from Corynebacterium glutamicum: a transcriptional repressor involved in L-lactate and sugar utilization.
Nucleic acids research - 1 Dec 2008
Gao Yong-Gui, Suzuki Hiroaki, Itou Hiroshi, Zhou Yong, Tanaka Yoshikazu, Wachi Masaaki, Watanabe Nobuhisa, Tanaka Isao, Yao Min
Abstract excerpt
LldR (CGL2915) from Corynebacterium glutamicum is a transcription factor belonging to the GntR family, which is typically involved in the regulation of oxidized substrates associated with amino acid metabolism. In the present study, the crystal structure of LldR was determined at 2.05-A resolution. The structure consists of N- and C-domains similar to those of FadR, but with distinct domain orientations. LldR and...
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