Article
KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise.
Physiological genomics - 8 Jan 2009
Argyropoulos George, Stütz Adrian M, Ilnytska Olha, Rice Treva, Teran-Garcia Margarita, Rao D C, Bouchard Claude, Rankinen Tuomo
Abstract excerpt
A genome-wide linkage scan for endurance training-induced changes in stroke volume detected a quantitative trait locus on chromosome 10p11 in white families of the HERITAGE Family Study. Dense microsatellite mapping narrowed down the linkage region to a 7 Mb area containing 16 known and 14 predicted genes. Association analyses with 90 single nucleotide polymorphisms (SNPs) provided suggestive evidence (P values...
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