Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans.

Journal of cell science - 1 Dec 2008

Yamashiro Sawako, Cox Elisabeth A, Baillie David L, Hardin Jeff D, Ono Shoichiro

Abstract excerpt

Sarcomeric organization of thin and thick filaments in striated muscle is important for the efficient generation of contractile forces. Sarcomeric actin filaments are uniform in their lengths and regularly arranged in a striated pattern. Tropomodulin caps the pointed end of actin filaments and is a crucial regulator of sarcomere assembly. Here, we report unexpected synergistic functions of tropomodulin with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Actin Depolymerizing Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Actins

Share to Caenorhabditis elegans Proteins

Share to Microfilament Proteins

Share to Microscopy, Fluorescence

Share to Profilins

Share to Sarcomeres

Source

Open in PubMed Open full text

Identifiers

PMID: 18984629
DOI: 10.1242/jcs.040477
PMCID: PMC2615493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans.PMID 18984629Read ↗

<i>Drosophila</i> Tropomodulin is required for multiple actin-dependent processes in myofiber assembly and maintenanceSemantic proximity Read ↗

The minus-end actin capping protein, UNC-94/tropomodulin, regulates development of the Caenorhabditis elegans intestine.Semantic proximity Read ↗

Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle.Semantic proximity Read ↗

Dual roles of tropomyosin as an F-actin stabilizer and a regulator of muscle contraction in Caenorhabditis elegans body wall muscle.Semantic proximity Read ↗

Tissue-Specific Functions of fem-2/PP2c Phosphatase and fhod-1/formin During Caenorhabditis elegans Embryonic Morphogenesis.Semantic proximity Read ↗

FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans.Semantic proximity Read ↗

Mechanism of actin filament pointed-end capping by tropomodulin.Semantic proximity Read ↗

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality.Semantic proximity Read ↗

Muscle arm development in Caenorhabditis elegans.Semantic proximity Read ↗

Enhancement of actin-depolymerizing factor/cofilin-dependent actin disassembly by actin-interacting protein 1 is required for organized actin filament assembly in the Caenorhabditis elegans body wall muscle.Semantic proximity Read ↗

Alteration of tropomyosin-binding properties of tropomodulin-1 affects its capping ability and localization in skeletal myocytes.Semantic proximity Read ↗

The role of leiomodin in actin dynamics: a new road or a secret gateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.