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Article

Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegans.

Journal of cell science - 1 Dec 2008

Yamashiro Sawako, Cox Elisabeth A, Baillie David L, Hardin Jeff D, Ono Shoichiro

Abstract excerpt

Sarcomeric organization of thin and thick filaments in striated muscle is important for the efficient generation of contractile forces. Sarcomeric actin filaments are uniform in their lengths and regularly arranged in a striated pattern. Tropomodulin caps the pointed end of actin filaments and is a crucial regulator of sarcomere assembly. Here, we report unexpected synergistic functions of tropomodulin with...

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Actin Cytoskeleton
Actin Depolymerizing Factors
Actins
Caenorhabditis elegans Proteins
Microfilament Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Fluorescence

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Identifiers

PMID: 18984629
DOI: 10.1242/jcs.040477
PMCID: PMC2615493

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