Article
Phenotypic impact of resistance mutations on etravirine susceptibility in HIV patients with prior failure to nonnucleoside analogues.
AIDS (London, England) - 12 Nov 2008
Poveda Eva, de Mendoza Carmen, Pattery Theresa, González María del Mar, Villacian Jorge, Soriano Vincent
Abstract excerpt
The phenotypic impact on etravirine susceptibility was examined in plasma specimens from 40 nonnucleoside reverse transcriptase inhibitor-experienced HIV patients with distinct nonnucleoside reverse transcriptase inhibitor resistance-associated mutations. Some etravirine resistance-associated mutations produced larger reductions in fold change than others. Y181C in combination with at least one etravirine...
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