Article
Diagnosis of canine B-cell chronic lymphoid leukemia with a CD21 negative phenotype using the LT21 clone CD21 antibody in flow cytometry: a case report.
BMC veterinary research - 26 Oct 2024
Choi Eun Wha, Jeong Yunho, Ahn Jin-Ok
Abstract excerpt
BACKGROUND: Chronic lymphoid leukemia (CLL) is a hematological disorder characterized by the clonal expansion of small mature lymphocytes that accumulate in the blood and bone marrow. CLL can arise from B-, T-, or natural killer cell clones. The cytological evaluation of blood smears is often the simplest and least invasive method for diagnosing lymphoid leukemia. Immunophenotyping is used to further subclassify...
Topics
- Female
- Animals
- Flow Cytometry
- Immunophenotyping
- Dogs
- Dog Diseases
- Leukemia, Lymphocytic, Chronic, B-Cell
- Receptors, Complement 3d
- Phenotype